A DOUBLE‐BLIND CROSSOVER STUDY COMPARING SODIUM CROMOGLYCATE EYE DROPS WITH PLACEBO IN THE TREATMENT OF CHRONIC CONJUNCTIVITIS

In a placebo controlled double-blind crossover study, 60 patients with chronic non-infections conjunctivitis were treated for 4 weeks with either sodium cromoglycate eye drops or with placebo followed by 4 weeks on the alternative treatment. The dose was one drop into each eye 4 times daily. The scores for a number of symptoms and signs were significantly lower after 4 weeks sodium cromoglycate treatment than after similar placebo treatment. In both the patients' and clinician's opinion significantly more patients responded to the active treatment than to the placebo treatment. At the end of the trial clinician recorded more preferences for sodium cromoglycate (27) than for placebo (9), and the difference was highly significant (P less than 0.01). No side effects were reported during the trial.