2003•Equine Veterinary JournalOpen access

Isolation and implantation of autologous equine mesenchymal stem cells from bone marrow into the superficial digital flexor tendon as a potential novel treatment

Roger K.W. Smith, Michelle Korda, Gordon William Blunn, Allen E. Goodship

Open full text 378 citations

Abstract

Antimicrobial resistance (AMR) evolution and onward transmission of resistance genes is impacted by interrelated biological and social drivers, with evidence and impacts observed across human, animal and environmental One Health domains.Systems-based research examining how food production impacts on AMR in complex agrifood systems is lacking, with little written on management approaches in the UK that might prevent and respond to this challenge.One approach is the creation of a transdisciplinary network to enhance capacity, capability and collaboration between agrifood-focused disciplines and stakeholders.This co-creation platform for network-wide systems-based activities would reduce inefficiencies in AMR-related activities around agrifood, providing a cross-cutting, cohesive community to deliver transformational guidance on relevant, practical agrifood solutions that add value by reducing AMR, antimicrobial usage and associated costs, and decreasing resultant environmental contamination by prioritising challenges, sharing knowledge and best practice, and cocreating practical solutions with key stakeholders.An online survey determined prospective network focus, structure and priorities, with responses analysed using mixed methods.Survey results suggested respondents have interests in synthesising data using systems-approaches and using certain disciplines such as 'social sciences' within network activities.There were disconnects in how and whom to work with on this, with generalised use of 'social science/scientists' but lack of disciplinary understanding (e. g., anthropology, sociology) suggesting disciplinary differences awareness-training is useful.A similar generalisation is seen for mathematics/statistics.There are strong interests in working with food system practitioners (e. g., farmers/vets), providing opportunities for farm/field visits/knowledge exchange, and human health, reflecting the need for farm-to-fork understanding of impacts.There were notable mentions of policy/governance, emphasising translational research desires to create meaningful change.Disciplines/fields did not always

Open-access reader

About this research paper

What this paper is about

Antimicrobial resistance (AMR) evolution and onward transmission of resistance genes is impacted by interrelated biological and social drivers, with evidence and impacts observed across human, animal and environmental One Health domains.Systems-based research examining how food production impacts on AMR in complex agrifood systems is lacking, with little written on management approaches in the UK that might prevent and respond to this challenge.One approach is the creation of a transdisciplinary network to enhance capacity, capability and collaboration between agrifood-focused disciplines and stakeholders.This co-creation platform for network-wide systems-based activities would reduce inefficiencies in AMR-related activities around agrifood, providing a cross-cutting, cohesive community to deliver transformational guidance on relevant, practical agrifood solutions that add value by reducing AMR, antimicrobial usage and associated costs, and decreasing resultant environmental contamination by prioritising challenges, sharing knowledge and best practice, and cocreating practical solutions with key stakeholders.An online survey determined prospective network focus, structure and priorities, with responses analysed using mixed methods.Survey results suggested respondents have interests in synthesising data using systems-approaches and using certain disciplines such as 'social sciences' within network activities.There were disconnects in how and whom to work with on this, with generalised use of 'social science/scientists' but lack of disciplinary understanding (e. g., anthropology, sociology) suggesting disciplinary differences awareness-training is useful.A similar generalisation is seen for mathematics/statistics.There are strong interests in working with food system practitioners (e. g., farmers/vets), providing opportunities for farm/field visits/knowledge exchange, and human health, reflecting the need for farm-to-fork understanding of impacts.There were notable mentions of policy/governance, emphasising translational research desires to create meaningful change.Disciplines/fields did not always

Why it matters

OpenAlex reports 378 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Antimicrobial resistance (AMR) evolution and onward transmission of resistance genes is impacted by interrelated biological and social drivers, with evidence and impacts observed across human, animal and environmental One Health domains.Systems-based research examining how food production impacts on AMR in complex agrifood systems is lacking, with little written on management approaches in the UK that might prevent and respond to this challenge.One approach is the creation of a transdisciplinary network to enhance capacity, capability and collaboration between agrifood-focused disciplines and stakeholders.This co-creation platform for network-wide systems-based activities would reduce inefficiencies in AMR-related activities around agrifood, providing a cross-cutting, cohesive community to deliver transformational guidance on relevant, practical agrifood solutions that add value by reducing AMR, antimicrobial usage and associated costs, and decreasing resultant environmental contamination by prioritising challenges, sharing knowledge and best practice, and cocreating practical solutions with key stakeholders.An online survey determined prospective network focus, structure and priorities, with responses analysed using mixed methods.Survey results suggested respondents have interests in synthesising data using systems-approaches and using certain disciplines such as 'social sciences' within network activities.There were disconnects in how and whom to work with on this, with generalised use of 'social science/scientists' but lack of disciplinary understanding (e. g., anthropology, sociology) suggesting disciplinary differences awareness-training is useful.A similar generalisation is seen for mathematics/statistics.There are strong interests in working with food system practitioners (e. g., farmers/vets), providing opportunities for farm/field visits/knowledge exchange, and human health, reflecting the need for farm-to-fork understanding of impacts.There were notable mentions of policy/governance, emphasising translational research desires to create meaningful change.Disciplines/fields did not always

Key concepts: Medicine, Orthopedic surgery, Veterinary medicine, Surgery

Related papers

Back to paper searchBrowse research topicsOriginal source
Isolation and implantation of autologous equine mesenchymal stem cells from bone marrow into the superficial digital flexor tendon as a potential novel treatment — Research Paper | ScholarLens