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1985•Neuropathology and Applied NeurobiologyRequires access

PRIMARY DEMYELINATION IN THE CENTRAL NERVOUS SYSTEM OF CATS

R. D. Cook, G.E. Wilcox

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Abstract

Abstract Cook R. D. & Wilcox G. E. (1985) Neuropathology and applied Neurobiology 11, 361–367 Primary demyelination in the central nervous system of cats Primary demyelinating lesions have been observed in the central nervous system of 16 (approximately 7%) of a total of 235 clinically normal cats. The size of the lesions varied from small perivascular lesions in white matter to a large lesion occupying the diameter of an optic nerve. Intracytoplasmic inclusions consisting of tubular structures were common to all lesions examined by electron microscopy. The features of these feline lesions are briefly compared with those seen in multiple sclerosis.

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Abstract Cook R. D. & Wilcox G. E. (1985) Neuropathology and applied Neurobiology 11, 361–367 Primary demyelination in the central nervous system of cats Primary demyelinating lesions have been observed in the central nervous system of 16 (approximately 7%) of a total of 235 clinically normal cats. The size of the lesions varied from small perivascular lesions in white matter to a large lesion occupying the diameter of an optic nerve. Intracytoplasmic inclusions consisting of tubular structures were common to all lesions examined by electron microscopy. The features of these feline lesions are briefly compared with those seen in multiple sclerosis.

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Available abstract

Abstract Cook R. D. & Wilcox G. E. (1985) Neuropathology and applied Neurobiology 11, 361–367 Primary demyelination in the central nervous system of cats Primary demyelinating lesions have been observed in the central nervous system of 16 (approximately 7%) of a total of 235 clinically normal cats. The size of the lesions varied from small perivascular lesions in white matter to a large lesion occupying the diameter of an optic nerve. Intracytoplasmic inclusions consisting of tubular structures were common to all lesions examined by electron microscopy. The features of these feline lesions are briefly compared with those seen in multiple sclerosis.

Key concepts: CATS, Neuropathology, Central nervous system, Pathology, White matter, Lesion, Multiple sclerosis, Medicine

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