1994•FEMS Microbiology LettersRequires access

The effect of gene tubC on the vegetative growth of benomyl-resistant strains ofAspergillus nidulans

Cristina de Andrade Monteiro, Sandra R.C. Pombeiro-Sponchiado, Nilce Maria Martinez-Rossi

Abstract

Two benomyl-resistant mutants, benD3 tubC41 and benD4 tubC42, of Aspergillus nidulans were isolated after UV treatment. The tubC mutations permitted good conidiation of these strains in culture media containing benomyl and were responsible for increasing their benomyl resistance levels. This implies that β3-tubulin, a product of the tubC gene, in addition to being involved in fungal conidiation, participates in the vegetative growth of the fungus. The tubC gene was located in linkage group I.

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Key concepts: Benomyl, Conidiation, Aspergillus nidulans, Biology, Fungus, Mutant, Gene, Microbiology