1976•The Journal of AntibioticsOpen access

Antibiotics produced by Streptomyces ficellus. II. Feldamycin and nojirimycin.

A. D. Argoudelis, Fritz Reusser, S. A. MIZSAK, L. BACZYNSKYJ

Abstract

Feldamycin, a new antibacterial agent, and nojirimycin, a previously described antibiotic have been isolated from cultures of Streptomyces ficellus. Feldamycin, C17H25N7O5, is an amphoteric compound which inhibits a variety of bacteria in vitro but is found to be ineffective in the treatment of experimental bacterial infections in mice. Nojirimycin (5-amino-5-deoxy-D-glucose) has been isolated previously from cultures of several species of streptomycetes.

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Key concepts: Antibiotics, Streptomyces, Bacteria, Streptomycetaceae, In vitro, Microbiology, Actinomycetales, Biology