2004•Molecular PharmacologyRequires access

Discovery of a Small Molecule Activator of the Human Ether-a-go-go-Related Gene (HERG) Cardiac K+ Channel

Jiesheng Kang, Xiaoliang Chen, Hongge Wang, Junzhi Ji, Hsien C. Cheng, Josephine Incardona, William Reynolds, Fabrice Viviani, Michel Tabart, David Rampe

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Key concepts: hERG, Dofetilide, Cardiac action potential, QT interval, Repolarization, Activator (genetics), Chemistry, Electrophysiology