2005•Cancer Chemotherapy and PharmacologyRequires access

Phase I study of the combination of topotecan and irinotecan in children with refractory solid tumors

Carlos Rodríguez‐Galindo, Kristine R. Crews, Clinton F. Stewart, Wayne L. Furman, John C. Panetta, Najat C. Daw, Alvida M. Cain, Ming Tan, Peter Houghton, Victor M. Santana

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Key concepts: Topotecan, Irinotecan, Camptothecin, Medicine, Pharmacology, SN-38, Pharmacokinetics, Neutropenia