2004•Nature MedicineOpen access

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A. Harrington, David Bebbington, Jeffrey R. Moore, Richele K. Rasmussen, Abi O Ajose-Adeogun, Tomoko Nakayama, Joanne A Graham, Cécile Demur, Thierry Hercend, Anita Diu‐Hercend, Michael Su, Julian M.C. Golec, Karen Miller

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Key concepts: Aurora inhibitor, Kinase, In vivo, Cancer research, Cytokinesis, Aurora kinase, Mitosis, Biology