1989NeurologyRequires access

Mild parkinsonism in persons exposed to 1‐methyl‐4‐phenyl‐1,2,3,6‐ tetrahydropyridine (MPTP)

James W. Tetrud, J. William Langston, Paul Garbe, A. James Ruttenber

Open publisher page 53 citations

Abstract

MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) produces moderate to severe parkinsonism in humans, but has not been reported to cause a syndrome similar to early Parkinson's disease. We now report 22 cases of mild parkinsonism resulting from exposure to MPTP.

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What this paper is about

MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) produces moderate to severe parkinsonism in humans, but has not been reported to cause a syndrome similar to early Parkinson's disease. We now report 22 cases of mild parkinsonism resulting from exposure to MPTP.

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OpenAlex reports 53 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) produces moderate to severe parkinsonism in humans, but has not been reported to cause a syndrome similar to early Parkinson's disease. We now report 22 cases of mild parkinsonism resulting from exposure to MPTP.

Key concepts: MPTP, Parkinsonism, Parkinson's disease, Medicine, Disease, Degenerative disease, Psychology, Internal medicine

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