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2013•The OncologistOpen access

Concise Drug Review: Azacitidine and Decitabine

Ellen J. B. Derissen, Jos H. Beijnen, Jan H.M. Schellens

Open full text 300 citations

Abstract

The introduction of the hypomethylating agents azacitidine and decitabine has been a major advancement in the treatment of patients with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia who are ineligible for more intensive treatments. This concise drug review summarizes the current state of treatment with azacitidine and decitabine.

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What this paper is about

The introduction of the hypomethylating agents azacitidine and decitabine has been a major advancement in the treatment of patients with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia who are ineligible for more intensive treatments. This concise drug review summarizes the current state of treatment with azacitidine and decitabine.

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OpenAlex reports 300 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The introduction of the hypomethylating agents azacitidine and decitabine has been a major advancement in the treatment of patients with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia who are ineligible for more intensive treatments. This concise drug review summarizes the current state of treatment with azacitidine and decitabine.

Key concepts: Azacitidine, Decitabine, Medicine, Myelodysplastic syndromes, Myeloid leukemia, Chronic myelomonocytic leukemia, Drug, Oncology

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