2005•Antimicrobial Agents and ChemotherapyOpen access

Selection of Cross-Resistance following Exposure of Pseudomonas aeruginosa Clinical Isolates to Ciprofloxacin or Cefepime

Samer A. Alyaseen, Kerryl E. Piper, Mark S. Rouse, James M. Steckelberg, Robin Patel

Abstract

Exposure of ciprofloxacin- and cefepime-susceptible Pseudomonas aeruginosa isolates to increasing concentrations of ciprofloxacin selected for ciprofloxacin resistance in 26/27 and cefepime nonsusceptibility in 7/27 isolates. Exposure of the isolates to increasing concentrations of cefepime selected for cefepime nonsusceptibility in 20/27 isolates but not for ciprofloxacin resistance.

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Available abstract

Key concepts: Cefepime, Ciprofloxacin, Pseudomonas aeruginosa, Microbiology, Pseudomonas, Biology, Pseudomonadales, Pseudomonadaceae