ScholarLens Back to search
2014•International Journal of Rheumatic DiseasesRequires access

Two elderly cases of familial mediterranean fever with rheumatoid arthritis

Naoki Matsuoka, Junko Iwanaga, Yasufumi Ichinose, Kaoru Fujiyama, Masahiko Tsuboi, Atsushi Kawakami, Kiyoshi Migita

Open publisher page 11 citations

Abstract

Familial Mediterranean fever (FMF) is a genetic autoinflammatory disorder that usually develops before 20 years of age and is characterized by periodic fever with serositis and arthritis. Both FMF and rheumatoid arthritis (RA) involve arthritis; however, their coexistence is rare. We describe two RA patients with an MEFV mutation in exon 2, who were diagnosed with FMF at an age of over 50 years. We also discuss the possibility that MEFV mutations could modulate RA disease activity.

About this research paper

What this paper is about

Familial Mediterranean fever (FMF) is a genetic autoinflammatory disorder that usually develops before 20 years of age and is characterized by periodic fever with serositis and arthritis. Both FMF and rheumatoid arthritis (RA) involve arthritis; however, their coexistence is rare. We describe two RA patients with an MEFV mutation in exon 2, who were diagnosed with FMF at an age of over 50 years. We also discuss the possibility that MEFV mutations could modulate RA disease activity.

Why it matters

OpenAlex reports 11 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Familial Mediterranean fever (FMF) is a genetic autoinflammatory disorder that usually develops before 20 years of age and is characterized by periodic fever with serositis and arthritis. Both FMF and rheumatoid arthritis (RA) involve arthritis; however, their coexistence is rare. We describe two RA patients with an MEFV mutation in exon 2, who were diagnosed with FMF at an age of over 50 years. We also discuss the possibility that MEFV mutations could modulate RA disease activity.

Key concepts: Familial Mediterranean fever, MEFV, Serositis, Medicine, Rheumatoid arthritis, Pyrin domain, Arthritis, Dermatology

Related papers

Related paper 1Related paper 2
Back to paper searchBrowse research topicsOriginal source
Two elderly cases of familial mediterranean fever with rheumatoid arthritis — Research Paper | ScholarLens