1990•Transactions of the Royal Society of Tropical Medicine and HygieneRequires access

Audiometry as a possible indicator of quinine plasma concentration during treatment of malaria

Kjell Karlsson, Urban Hellgren, Gunnar Alván, Lars Rombo

Abstract

The spread of chloroquine-resistant malaria has led to a resurgence of quinine in clinical use. One of the well-known side effects of quinine, reversible hearing loss, is closely related to the plasma concentration. We suggest that this hearing effect could be used as an aid in therapy control when quinine drug assay is not available.

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Key concepts: Medicine, University hospital, Quinine, MEDLINE, Malaria, Family medicine, Library science, Political science