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2010•Geriatrics and gerontology international/Geriatrics & gerontology internationalRequires access

Two cases with solitary pulmonary nodule due to non‐tuberculous mycobacterial infection showing intense 18F‐fluorodeoxyglucose uptake on positron emission tomography scan

Eriko Kawate, Mariko Yamazaki, Tadashi Kohno, Sakashi Fujimori, Hideki Takahashi

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Abstract

We report an 81-year-old man and a 65-year-old woman with a solitary pulmonary nodule (SPN) due to infection with non-tuberculous mycobacteria (NTM). In each case, the nodule showed a high (18)F-fluorodeoxyglucose (FDG) uptake with the maximum standardized uptake values (SUV) of 13.2 and 4.8 on positron emission tomography (PET) imaging, respectively. Both cases required partial lung resection for confirmation of the histological diagnosis. A review of six reported patients with SPN due to NTM infections showed that the SUV of FDG was more than 4.0 in the nodules of all cases. Positive results on FDG-PET should be interpreted cautiously when evaluating SPN, especially in patients having predisposing factors for NTM infections.

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What this paper is about

We report an 81-year-old man and a 65-year-old woman with a solitary pulmonary nodule (SPN) due to infection with non-tuberculous mycobacteria (NTM). In each case, the nodule showed a high (18)F-fluorodeoxyglucose (FDG) uptake with the maximum standardized uptake values (SUV) of 13.2 and 4.8 on positron emission tomography (PET) imaging, respectively. Both cases required partial lung resection for confirmation of the histological diagnosis. A review of six reported patients with SPN due to NTM infections showed that the SUV of FDG was more than 4.0 in the nodules of all cases. Positive results on FDG-PET should be interpreted cautiously when evaluating SPN, especially in patients having predisposing factors for NTM infections.

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Available abstract

We report an 81-year-old man and a 65-year-old woman with a solitary pulmonary nodule (SPN) due to infection with non-tuberculous mycobacteria (NTM). In each case, the nodule showed a high (18)F-fluorodeoxyglucose (FDG) uptake with the maximum standardized uptake values (SUV) of 13.2 and 4.8 on positron emission tomography (PET) imaging, respectively. Both cases required partial lung resection for confirmation of the histological diagnosis. A review of six reported patients with SPN due to NTM infections showed that the SUV of FDG was more than 4.0 in the nodules of all cases. Positive results on FDG-PET should be interpreted cautiously when evaluating SPN, especially in patients having predisposing factors for NTM infections.

Key concepts: Medicine, Positron emission tomography, Fluorodeoxyglucose, Positron emission, Positron, Nuclear medicine, Nodule (geology), Positron Emission Tomography-Computed Tomography

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Two cases with solitary pulmonary nodule due to non‐tuberculous mycobacterial infection showing intense 18F‐fluorodeoxyglucose uptake on positron emission tomography scan — Research Paper | ScholarLens