1978•Acta Pharmacologica et ToxicologicaRequires access

Effects of DDT (Chlorophenotane) Administration on Glucose Uptake and Brush Border Enzymes in Monkey Intestine

Akhtar Mahmood, Neeraj Agarwal, Sankar Nath Sanyal, D. Subrahmanyam

Abstract

A considerable increase occurs in D-glucose uptake and brush border sucrase and lactase activities in the intestine of monkeys treated with a single oral dose of DDT. Brush border alkaline phosphatase activity remains unaffected in the pesticide treated animals. In vitro addiction of DDT has no effect on the sugar absorption and disaccharidase activities.

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Key concepts: Disaccharidase, Brush border, Lactase, Sucrase, Alkaline phosphatase, Brush, Internal medicine, Endocrinology