Time Intensity Factors and Whole Body Irradiation

Total body irradiation was given to mice on a daily basis and the equivalent doses to achieve L.D.50 effects were compared for overall times up to 20 days. A second set of experiments was done to find the recovery rate from a constant initial dose of radiation, comparing L.D.50 values. The graphs of recovery for these two sets of experiments are contrasted. The significance of these experiments in relation to recovery from total body radiation exposure is discussed. The rate of recovery from total body irradiation is compared with that for other biological materials.