2003•Nature ImmunologyRequires access

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

Kasper H. N. Hoebe, Edith M. Janssen, Sung Ouk Kim, Lena Alexopoulou, Richard Anthony Flavell, Jiahuai Han, Bruce Beutler

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Key concepts: TRIF, TLR3, Cell biology, Toll-like receptor, Downregulation and upregulation, Autocrine signalling, Interferon, Signal transduction

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Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways — Research Paper | ScholarLens