Comparison of glycated albumin levels before and after periodontal treatment in type 2 diabetes patients with periodontitis

Background: Periodontal disease is closely related to type 2 diabetes and is an important complication of diabetes. \n \nAim: This study aimed to investigate the effect of periodontal treatment on levels of blood glucose (Glu) and glycated albumin (GA) among patients with type 2 diabetes and periodontal disease. \n \nMethods: A total of 150 patients with type 2 diabetes and periodontal disease were selected and divided into two groups according to their GA levels. Group A was a well-controlled diabetic group and group B was uncontrolled. Their probing depth (PD), attachment loss (AL), the value of glucose and GA were analyzed before periodontal treatment and every two weeks in two months interval after. \n \nResults: There was a significant difference in periodontal condition between groups A and B (P <0.01). The periodontal condition for both groups was significantly (P <0.01) improved after periodontal therapy. The effect of treatment in group A was more pronounced than group B, and the difference was significant (P <0.01). After the periodontal treatment, Glu and GA were reduced significantly in both groups (P <0.05). \n \nConclusion: Periodontal condition is related to the control of glucose level among patients with type 2 diabetes and periodontal disease. Periodontal treatment can effectively reduce the level of glucose and GA as well as it improves the periodontal condition in type-2 diabetes patients with periodontal disease.