2008Nature Structural & Molecular BiologyOpen access

The structure of CCT–Hsc70NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin

Jorge Cuéllar, Jaime Martín‐Benito, Sjors H. W. Scheres, Rui Sousa, Fernando Moro, Eduardo López‐Viñas, Paulino Gómez‐Puertas, Arturo Muga, José L. Carrascosa, José Valpuesta

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Key concepts: Chaperonin, GroEL, Chaperone (clinical), Co-chaperone, Protein folding, Hsp70, Heat shock protein, Protein subunit

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