1970•The Japanese Journal of PhysiologyOpen access

A PRELIMINARY NOTE ON THE ADRENERGIC MECHANISM OF SWEAT SECRETION AND THE SWEAT ELECTROLYTE CONCENTRATION IN MAN

Kimio Ikai, Kohachiro Sugiyama, Yoshihiko Otsuka, Hatsuo Nitta

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Abstract

1. Analysis of electrolyte composition of human body sweat induced by simultaneous iontophoresis of noradrenaline and pilocarpine (noradrenaline sweating) revealed increased sodium and chloride concentrations as well as increased Na/K ratio, compared with the control sweating induced by pilocarpine alone.2. Human body sweat induced by simultaneous iontophoresis of adrenaline and pilocarpine (adrenaline sweating) seems to present an increased sodium and chloride concentrations as well as increased Na/K ratio, while the difference from the control sweating is not statistically significant except for Na/K ratio.3. On the basis of these findings on the human body sweat, and of the similar findings in the palmar sweat of the monkey, the alpha and beta adrenergic receptor mechanisms to control the sweat electrolyte concentration, was suggested to be present in the sweat gland of man as in the monkey.

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1. Analysis of electrolyte composition of human body sweat induced by simultaneous iontophoresis of noradrenaline and pilocarpine (noradrenaline sweating) revealed increased sodium and chloride concentrations as well as increased Na/K ratio, compared with the control sweating induced by pilocarpine alone.2. Human body sweat induced by simultaneous iontophoresis of adrenaline and pilocarpine (adrenaline sweating) seems to present an increased sodium and chloride concentrations as well as increased Na/K ratio, while the difference from the control sweating is not statistically significant except for Na/K ratio.3. On the basis of these findings on the human body sweat, and of the similar findings in the palmar sweat of the monkey, the alpha and beta adrenergic receptor mechanisms to control the sweat electrolyte concentration, was suggested to be present in the sweat gland of man as in the monkey.

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1. Analysis of electrolyte composition of human body sweat induced by simultaneous iontophoresis of noradrenaline and pilocarpine (noradrenaline sweating) revealed increased sodium and chloride concentrations as well as increased Na/K ratio, compared with the control sweating induced by pilocarpine alone.2. Human body sweat induced by simultaneous iontophoresis of adrenaline and pilocarpine (adrenaline sweating) seems to present an increased sodium and chloride concentrations as well as increased Na/K ratio, while the difference from the control sweating is not statistically significant except for Na/K ratio.3. On the basis of these findings on the human body sweat, and of the similar findings in the palmar sweat of the monkey, the alpha and beta adrenergic receptor mechanisms to control the sweat electrolyte concentration, was suggested to be present in the sweat gland of man as in the monkey.

Key concepts: Pilocarpine, SWEAT, Iontophoresis, Endocrinology, Internal medicine, Sodium, Chemistry, Electrolyte

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