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1999•Analytical LettersRequires access

End-Column Amperometric Detection of 5-Fluorouracil by Capillary Zone Electrophoresis with a Carbon Fiber Microelectrode

Tianyan You, Xiaoqing Wang, Xiurong Yang, Erkang Wang

Open publisher page 7 citations

Abstract

A rapid and sensitive detection method for the determination of 5-fluorouracil(5-FU) in real samples such as human urine and bovine serum albumin (BSA) was described. A carbon fiber microdisk electrode was used to perform end-column amperometric detection in capillary zone electrophoresis. The detection limit was as low as 2.5x10−7 M and the wider linear range for the concentration was between 5x10−6 and 1x10−4 M with a correlation coefficient of 0.995.

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What this paper is about

A rapid and sensitive detection method for the determination of 5-fluorouracil(5-FU) in real samples such as human urine and bovine serum albumin (BSA) was described. A carbon fiber microdisk electrode was used to perform end-column amperometric detection in capillary zone electrophoresis. The detection limit was as low as 2.5x10−7 M and the wider linear range for the concentration was between 5x10−6 and 1x10−4 M with a correlation coefficient of 0.995.

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OpenAlex reports 7 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A rapid and sensitive detection method for the determination of 5-fluorouracil(5-FU) in real samples such as human urine and bovine serum albumin (BSA) was described. A carbon fiber microdisk electrode was used to perform end-column amperometric detection in capillary zone electrophoresis. The detection limit was as low as 2.5x10−7 M and the wider linear range for the concentration was between 5x10−6 and 1x10−4 M with a correlation coefficient of 0.995.

Key concepts: Amperometry, Chemistry, Capillary electrophoresis, Detection limit, Chromatography, Microelectrode, Analytical Chemistry (journal), Linear range

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End-Column Amperometric Detection of 5-Fluorouracil by Capillary Zone Electrophoresis with a Carbon Fiber Microelectrode — Research Paper | ScholarLens