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2014•Case Reports in Internal MedicineOpen access

Chronic eosinophilic leukemia transformation into acute myeloid leukemia with monocytic differentiation

James Joseph Driscoll, Mohamed A.Y. Abdel Malek, Douaa Mohammed Sayed, Youseryeia A. Ahmad

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Abstract

We present a rare case of a patient that presented with a highly elevated total leukocytic count, abnormally high eosinophils and increased number of blasts that was diagnosed as chronic eosinophilic leukemia. The blast cell count did not reach the threshold to diagnose acute leukemia. Over 6 months, the case progressed to acute myeloid leukemia with normal total leukocyte count but high percentage of blast cells and decreased percentage of eosinophils.

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What this paper is about

We present a rare case of a patient that presented with a highly elevated total leukocytic count, abnormally high eosinophils and increased number of blasts that was diagnosed as chronic eosinophilic leukemia. The blast cell count did not reach the threshold to diagnose acute leukemia. Over 6 months, the case progressed to acute myeloid leukemia with normal total leukocyte count but high percentage of blast cells and decreased percentage of eosinophils.

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Available abstract

We present a rare case of a patient that presented with a highly elevated total leukocytic count, abnormally high eosinophils and increased number of blasts that was diagnosed as chronic eosinophilic leukemia. The blast cell count did not reach the threshold to diagnose acute leukemia. Over 6 months, the case progressed to acute myeloid leukemia with normal total leukocyte count but high percentage of blast cells and decreased percentage of eosinophils.

Key concepts: Myeloid leukemia, Eosinophilic, Medicine, Leukemia, Eosinophilia, Acute monocytic leukemia, Acute leukemia, Precursor cell

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