Femoral arteriotomy closure using the Mynx vascular closure device: a profile of device efficacy and complications

Percutaneous coronary interventions, transarterial peripheral vascular interventions and neuroendovascular procedures are commonly performed procedures, with transfemoral access representing the preferred approach. Manual compression has traditionally been the mainstay of achieving femoral arteriotomy closure; however, numerous vascular closure devices have been developed as an alternative to manual compression and extended bed rest. Initially introduced in 2007, the Mynx product family of vascular closure devices (Access Closure, CA, USA) are one of the most popular devices on the market in the USA. The Mynx device consists of a catheter with a polyethylene glycol sealant designed to achieve suture-free arterial hemostasis by delivering a conformable, water-soluble sealant into the extravascular space over the arteriotomy. Given the increasing number of transarterial interventional procedures, a thorough understanding of device efficacy, as well as patient and procedural characteristics that predict fail...