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1987•British Journal of Clinical PharmacologyOpen access

Does regular treatment with ketotifen inhibit bronchoconstriction induced by isocapnic hyperventilation?

Paul Rafferty, P.M. Tweeddale, RJ Ferguson, Beverley‐Ann Biggs, Ian W B Grant

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Abstract

Eight asthmatic patients completed a 12-week, double-blind, placebo controlled study to assess the efficacy of ketotifen, 1 mg twice daily, in the inhibition of bronchoconstriction induced by isocapnic hyperventilation (IH). There was no significant difference in the degree of bronchoconstriction produced by IH after treatment with ketotifen or placebo.

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What this paper is about

Eight asthmatic patients completed a 12-week, double-blind, placebo controlled study to assess the efficacy of ketotifen, 1 mg twice daily, in the inhibition of bronchoconstriction induced by isocapnic hyperventilation (IH). There was no significant difference in the degree of bronchoconstriction produced by IH after treatment with ketotifen or placebo.

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Available abstract

Eight asthmatic patients completed a 12-week, double-blind, placebo controlled study to assess the efficacy of ketotifen, 1 mg twice daily, in the inhibition of bronchoconstriction induced by isocapnic hyperventilation (IH). There was no significant difference in the degree of bronchoconstriction produced by IH after treatment with ketotifen or placebo.

Key concepts: Ketotifen, Bronchoconstriction, Hyperventilation, Placebo, Anesthesia, Medicine, Asthma, Internal medicine

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Does regular treatment with ketotifen inhibit bronchoconstriction induced by isocapnic hyperventilation? — Research Paper | ScholarLens