Long-term efficacy and safety of once daily treatment of chronic plaque psoriasis with tacalcitol ointment

Vitamin D3 analogues represent a major innovation in the treatment of psoriasis today [1-4]. During the last 5 years, calcipotriol (50 µg/g) ointment has become a first line therapy for this condition. Calcipotriol treatment is generally accepted for long-term management of psoriasis, although irritation of the skin has been experienced by 25% of the patients and required discontinuation of treatment in approximately 6% of the [...]