ScholarLens Back to search
2006•Infection and ImmunityOpen access

Mouse and Human Cell Activation by N -Dodecanoyl- dl -Homoserine Lactone, a Chromobacterium violaceum Autoinducer

Kazunori Gomi, Toshiaki Kikuchi, Yutaka Tokue, Shigeru Fujimura, Akiko Uehara, Haruhiko Takada, Akira Watanabe, Toshihiro Nukiwa

Open full text 11 citations

Abstract

Chromobacterium violaceum produces autoinducers, including homoserine lactones (HSLs), for genetic regulation. Among the seven HSLs derived from C. violaceum we evaluated, only C(12)-HSL stimulated the production of inflammatory cytokines in mammalian monocytic cell lines through the activation of the NF-kappaB signaling pathway besides their quorum-sensing role, like 3-oxo-C(12)-HSL from Pseudomonas aeruginosa.

About this research paper

What this paper is about

Chromobacterium violaceum produces autoinducers, including homoserine lactones (HSLs), for genetic regulation. Among the seven HSLs derived from C. violaceum we evaluated, only C(12)-HSL stimulated the production of inflammatory cytokines in mammalian monocytic cell lines through the activation of the NF-kappaB signaling pathway besides their quorum-sensing role, like 3-oxo-C(12)-HSL from Pseudomonas aeruginosa.

Why it matters

OpenAlex reports 11 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Chromobacterium violaceum produces autoinducers, including homoserine lactones (HSLs), for genetic regulation. Among the seven HSLs derived from C. violaceum we evaluated, only C(12)-HSL stimulated the production of inflammatory cytokines in mammalian monocytic cell lines through the activation of the NF-kappaB signaling pathway besides their quorum-sensing role, like 3-oxo-C(12)-HSL from Pseudomonas aeruginosa.

Key concepts: Chromobacterium violaceum, Quorum sensing, Autoinducer, Homoserine, Biology, Microbiology, Pseudomonas aeruginosa, Bacteria

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Mouse and Human Cell Activation by N -Dodecanoyl- dl -Homoserine Lactone, a Chromobacterium violaceum Autoinducer — Research Paper | ScholarLens