Mandibular central giant cell granuloma associated with sclerosing osteomyelitis of Garrè (periostitis ossificans). Case report

Garrè's sclerosing osteomyelitis or periostitis ossificans with a radiographic 'onion skin' appearance is a separate clinical entity. The new bone formation underneath the periosteum is a response of periosteum to stimulation by low grade infection. This may occur in a variety of other developmental, metabolic, inflammatory and neoplastic diseases of bone. A case of mandibular giant cell granuloma of a central type associated with Garrè's sclerosing osteomyelitis is presented and the literature is reviewed.