Clinical associations of vitiligo

Summary Vitiligo, a common skin condition, has been reported in association with thyroid disease, pernicious anaemia, carcinoma of the stomach, Addison’s disease and diabetes mellitus. Some subjects with vitiligo can be shown to possess circulating antibodies to thyroid gland, thyroglobulin, gastric parietal cells and adrenal gland, even in the absence of disease. Vitiligo is evidently another ‘skin-marker of internal disease’.