The issues of radiation therapy of oncology patients from the viewpoint of radiobiology

Based on the analysis of literature and our research, this paper discusses the following issues of radiotherapy from the viewpoint of radiobiology: radioresistance of tumor, including stem, cells; secondary tumors of radiogenesis, the ratio of radiosensitivity of tumors and tumor-bearing individual radiosensitivity of the organism, co-mutagenesis in irradiated cells, personalized therapy