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2000•Antimicrobial Agents and ChemotherapyOpen access

In Vitro Activity of ABT-773, a New Ketolide, against Recent Clinical Isolates of Streptococcus pneumoniae , Haemophilus influenzae , and Moraxella catarrhalis

Angela B. Brueggemann, Gary V. Doern, Holly K. Huynh, Elizabeth M. Wingert, Paul R. Rhomberg

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Abstract

The in vitro activity of ABT-773 was evaluated against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis isolates. ABT-773 was the most active antimicrobial tested against S. pneumoniae. ABT-773 and azithromycin were equivalent in activity against H. influenzae and M. catarrhalis and more active than either clarithromycin or erythromycin.

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What this paper is about

The in vitro activity of ABT-773 was evaluated against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis isolates. ABT-773 was the most active antimicrobial tested against S. pneumoniae. ABT-773 and azithromycin were equivalent in activity against H. influenzae and M. catarrhalis and more active than either clarithromycin or erythromycin.

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Available abstract

The in vitro activity of ABT-773 was evaluated against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis isolates. ABT-773 was the most active antimicrobial tested against S. pneumoniae. ABT-773 and azithromycin were equivalent in activity against H. influenzae and M. catarrhalis and more active than either clarithromycin or erythromycin.

Key concepts: Moraxella catarrhalis, Haemophilus influenzae, Streptococcus pneumoniae, Moraxella (Branhamella) catarrhalis, Microbiology, Ketolide, Moraxella, Erythromycin

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In Vitro Activity of ABT-773, a New Ketolide, against Recent Clinical Isolates of Streptococcus pneumoniae , Haemophilus influenzae , and Moraxella catarrhalis — Research Paper | ScholarLens