1970•Journal of General MicrobiologyRequires access

Studies on Cholera Toxin and Antitoxin

J. Ungar, M. Stanić, N Chariatte, S Varallyay

Abstract

SUMMARY: The preparation, purification and properties of cholera toxin type 2 are described. When the toxin was given to experimental animals it induced a high level of toxin-neutralizing antibodies. Cholera toxoid given to human volunteers induced antibodies consisting of agglutinins, vibriocidal and toxin-neutralizing antibodies. The relevant titres depended on the purity of the antigen administered.

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Available abstract

Key concepts: Antitoxin, Cholera toxin, Toxin, Cholera, Toxoid, Cholera vaccine, Vibrio cholerae, Antibody