Karen M. Bromfield, Henrik Gradén, Daniel P. Hagberg, Thomas Olsson, Nina Kann
Abstract
A novel synthetic route towards oseltamivir, an influenza neuraminidase inhibitor, has been achieved employing a cationic iron carbonyl complex, providing an alternate pathway with the potential to access diverse analogues.
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A novel synthetic route towards oseltamivir, an influenza neuraminidase inhibitor, has been achieved employing a cationic iron carbonyl complex, providing an alternate pathway with the potential to access diverse analogues.
Key concepts: Oseltamivir, Neuraminidase inhibitor, Neuraminidase, Chemistry, Cationic polymerization, Zanamivir, Virology, Combinatorial chemistry