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2002•Journal of Clinical MicrobiologyOpen access

Evidence of the Presence of IS 1245 and IS 1311 or Closely Related Insertion Elements in Nontuberculous Mycobacteria outside of the Mycobacterium avium Complex

Andreas P. Keller, Marjorie L. Beggs, Beate Amthor, Fabian Bruns, Peter Meißner, Walter Haas

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Abstract

A PCR assay based on the simultaneous detection of IS1245 and IS1311 was developed and used to determine the host range of these insertion elements. Specific PCR products were observed in Mycobacterium malmoense, Mycobacterium scrofulaceum, and Mycobacterium nonchromogenicum, indicating that IS1245 and IS1311 are not limited to the Mycobacterium avium complex.

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What this paper is about

A PCR assay based on the simultaneous detection of IS1245 and IS1311 was developed and used to determine the host range of these insertion elements. Specific PCR products were observed in Mycobacterium malmoense, Mycobacterium scrofulaceum, and Mycobacterium nonchromogenicum, indicating that IS1245 and IS1311 are not limited to the Mycobacterium avium complex.

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Available abstract

A PCR assay based on the simultaneous detection of IS1245 and IS1311 was developed and used to determine the host range of these insertion elements. Specific PCR products were observed in Mycobacterium malmoense, Mycobacterium scrofulaceum, and Mycobacterium nonchromogenicum, indicating that IS1245 and IS1311 are not limited to the Mycobacterium avium complex.

Key concepts: Nontuberculous mycobacteria, Mycobacterium, Mycobacterium avium complex, Microbiology, Biology, Mycobacterium Infections, Polymerase chain reaction, Virology

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Evidence of the Presence of IS 1245 and IS 1311 or Closely Related Insertion Elements in Nontuberculous Mycobacteria outside of the Mycobacterium avium Complex — Research Paper | ScholarLens