ScholarLens Back to search
1984•Clinical and Experimental DermatologyRequires access

Response of rosacea to isotretinoin

J.R. Marsden, Sam Shuster, M. Neugebauer

Open publisher page 45 citations

Abstract

We have treated seven patients with severe rosacea with 1 mg kg−1 day−1 isotretinoin for 12 weeks. There were large reductions in numbers of papules and pustules (P < 0.001) small decreases in measurements of erythema (P < 0.01) and median values for severity were lower during and after treatment. There was evidence of relapse by 8 weeks after stopping isotretinoin. Side‐effects were well tolerated and increases in serum lipids and indices of liver function had reversed by 4 weeks after treatment. We conclude that isotretinoin is effective in rosacea.

About this research paper

What this paper is about

We have treated seven patients with severe rosacea with 1 mg kg−1 day−1 isotretinoin for 12 weeks. There were large reductions in numbers of papules and pustules (P < 0.001) small decreases in measurements of erythema (P < 0.01) and median values for severity were lower during and after treatment. There was evidence of relapse by 8 weeks after stopping isotretinoin. Side‐effects were well tolerated and increases in serum lipids and indices of liver function had reversed by 4 weeks after treatment. We conclude that isotretinoin is effective in rosacea.

Why it matters

OpenAlex reports 45 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

We have treated seven patients with severe rosacea with 1 mg kg−1 day−1 isotretinoin for 12 weeks. There were large reductions in numbers of papules and pustules (P < 0.001) small decreases in measurements of erythema (P < 0.01) and median values for severity were lower during and after treatment. There was evidence of relapse by 8 weeks after stopping isotretinoin. Side‐effects were well tolerated and increases in serum lipids and indices of liver function had reversed by 4 weeks after treatment. We conclude that isotretinoin is effective in rosacea.

Key concepts: Isotretinoin, Rosacea, Medicine, Erythema, Dermatology, Gastroenterology, Internal medicine, Acne

Related papers

Related paper 1Related paper 2
Back to paper searchBrowse research topicsOriginal source
Response of rosacea to isotretinoin — Research Paper | ScholarLens