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Clobazam maintenance among methadone maintenance patients with problematic benzodiazepine use: five case studies

WENDY A. WICKES, Shane G Darke, Joanne E Ross

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Abstract

The aim of this pilot study was to determine the potential of maintenance with clobazam in patients on methadone who we also benzodiazepine dependent. Five individuals we recruited and four were maintained on clobazam for a minimum of 3 months prior to reduction. Three subjects we abstinent from other benzodiazepines at 3 months. Clobazam was given as a single daily dose and was reported by the clients as less sedating than diazepam There is potential for clobazam to be used as a maintenance benzodiazepine.

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What this paper is about

The aim of this pilot study was to determine the potential of maintenance with clobazam in patients on methadone who we also benzodiazepine dependent. Five individuals we recruited and four were maintained on clobazam for a minimum of 3 months prior to reduction. Three subjects we abstinent from other benzodiazepines at 3 months. Clobazam was given as a single daily dose and was reported by the clients as less sedating than diazepam There is potential for clobazam to be used as a maintenance benzodiazepine.

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OpenAlex reports 9 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The aim of this pilot study was to determine the potential of maintenance with clobazam in patients on methadone who we also benzodiazepine dependent. Five individuals we recruited and four were maintained on clobazam for a minimum of 3 months prior to reduction. Three subjects we abstinent from other benzodiazepines at 3 months. Clobazam was given as a single daily dose and was reported by the clients as less sedating than diazepam There is potential for clobazam to be used as a maintenance benzodiazepine.

Key concepts: Clobazam, Benzodiazepine, Methadone maintenance, Methadone, Medicine, Anti-Anxiety Agents, Diazepam, Anesthesia

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