1973•The Tohoku Journal of Experimental MedicineOpen access

Choline Phosphokinase, Phosphorylcholine Cytidyltransferase and CDP-choline: 1, 2-diglyceride Cholinephosphotransferase Activity in Developing Rat Lung

Nobukazu Chida, Haruko Hirono, Yasuhiro Nishimura, Tsuneo Arakawa

Abstract

CHIDA, N., HIRONO, H., NISHIMURA, Y. and ARAKAWA, Ts., Choline Phosphokinase, Phosphorylcholine Cytidyltransferase and CDP-choline-1, 2-diglyceride Cholinephosphotransferase Activity in Developing Rat Lung. Tohoku J. exp. Med., 1973, 110 (3), 273-282-Incorporation of choline-methyl-14C into phosphorylcholine, CDP-choline, and phosphatidylcholine by lung tissue of developing rats was studied. Choline phosphokinase, phosphorylcholine cytidyltransferase, and CDP-choline: 1, 2-diglyceride choline phosphotransferase were determined in the lung tissue of developing rats. Results indicated that phosphorylcholine cytidyltransferase was the rate-limiting enzyme in the reactions-choline→phosphoryl-choline→CDP-choline→phosphatidylcholine

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Key concepts: Phosphorylcholine, Choline, Choline kinase, Phosphatidylcholine, Chemistry, PLD2, Biochemistry, Phosphocholine