ScholarLens Back to search
2011•Future VirologyRequires access

Host Response to Chikungunya Virus and Perspectives for Immune-Based Therapies

Terk‐Shin Teng, Yiu‐Wing Kam, Jeslin J. L. Tan, Lisa F. P. Ng

Open publisher page 16 citations

Abstract

Chikungunya virus (CHIKV), a dormant ‘old world’ alphavirus, has warranted worldwide research attention due to the explosive nature of its outbreak events during 2004–2008. Despite being around for more than 50 years, CHIKV still remains elusive compared with other members of the alphavirus family. In light of the potential threat that CHIKV poses, encouraging efforts are taking place to understand CHIKV from different perspectives. This review summarizes our current clinical, pathological and immunological knowledge of CHIKV and examines how we can utilize our understanding of host response for therapeutic strategies.

About this research paper

What this paper is about

Chikungunya virus (CHIKV), a dormant ‘old world’ alphavirus, has warranted worldwide research attention due to the explosive nature of its outbreak events during 2004–2008. Despite being around for more than 50 years, CHIKV still remains elusive compared with other members of the alphavirus family. In light of the potential threat that CHIKV poses, encouraging efforts are taking place to understand CHIKV from different perspectives. This review summarizes our current clinical, pathological and immunological knowledge of CHIKV and examines how we can utilize our understanding of host response for therapeutic strategies.

Why it matters

OpenAlex reports 16 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Chikungunya virus (CHIKV), a dormant ‘old world’ alphavirus, has warranted worldwide research attention due to the explosive nature of its outbreak events during 2004–2008. Despite being around for more than 50 years, CHIKV still remains elusive compared with other members of the alphavirus family. In light of the potential threat that CHIKV poses, encouraging efforts are taking place to understand CHIKV from different perspectives. This review summarizes our current clinical, pathological and immunological knowledge of CHIKV and examines how we can utilize our understanding of host response for therapeutic strategies.

Key concepts: Chikungunya, Alphavirus, Alphavirus infection, Virus, Virology, Outbreak, Immune system, Host (biology)

Related papers

Related paper 1Related paper 2
Back to paper searchBrowse research topicsOriginal source
Host Response to Chikungunya Virus and Perspectives for Immune-Based Therapies — Research Paper | ScholarLens