2009•Journal of Pharmacology and Experimental TherapeuticsRequires access

Resistance to Mitogen-Activated Protein Kinase Kinase (MEK) Inhibitors Correlates with Up-Regulation of the MEK/Extracellular Signal-Regulated Kinase Pathway in Hepatocellular Carcinoma Cells

Michele Yip-Schneider, Patrick Klein, Sabrina Wentz, Amer M. Zeni, Alex Menze, C. Max Schmidt

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Key concepts: ASK1, Mitogen-activated protein kinase kinase, Protein kinase A, Cyclin-dependent kinase 2, Cyclin-dependent kinase 9, MAP2K7, MAP kinase kinase kinase, Kinase

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Resistance to Mitogen-Activated Protein Kinase Kinase (MEK) Inhibitors Correlates with Up-Regulation of the MEK/Extracellular Signal-Regulated Kinase Pathway in Hepatocellular Carcinoma Cells — Research Paper | ScholarLens