Performance of the Abbott RealTime and Roche Cobas TaqMan Hepatitis C Virus (HCV) Assays for Quantification of HCV Genotypes
Heidi LaRue, Lisa Rigali, Joan-Miquel Balada-Llasat, Preeti Pancholi
Abstract
Heidi LaRue, Lisa Rigali, Joan-Miquel Balada-Llasat, Preeti Pancholi
Abstract
We evaluated the Abbott RealTime (ART) and Roche Cobas TaqMan Hepatitis C virus (HCV) viral load assays for quantification of HCV genotypes in patient specimens. The ART HCV assay was a more sensitive and precise tool for accurate HCV viral load quantification across the HCV genotypes tested, especially genotype 1b.
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We evaluated the Abbott RealTime (ART) and Roche Cobas TaqMan Hepatitis C virus (HCV) viral load assays for quantification of HCV genotypes in patient specimens. The ART HCV assay was a more sensitive and precise tool for accurate HCV viral load quantification across the HCV genotypes tested, especially genotype 1b.
Key concepts: TaqMan, Virology, Hepatitis C virus, Genotype, Viral load, Hepacivirus, Hepatitis C, Flaviviridae