2011•Clinical Pharmacology & TherapeuticsRequires access
Investigative Clinical Pharmacology
Colin T. Dollery
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Abstract
Clinical pharmacology is an essential discipline in the development of new medicines, but the closely specified requirements of pharmaceutical industry protocols and regulatory reviewers have limited the opportunities for curiosity-driven research. Realization is growing that there is so much that is not known about the mechanisms underlying human disease and the actions of medicines on them that research of a more exploratory kind, namely, investigative clinical pharmacology, is a priority.