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2007•Journal of Oral Pathology and MedicineRequires access

Proliferative verrucous leukoplakia and its progression to oral carcinoma: report of three cases

Thomas Hellman Morton, Robert J. Cabay, Joel Brian Epstein

Open publisher page 53 citations

Abstract

Proliferative verrucous leukoplakia (PVL) is a distinct clinical form of oral leukoplakia defined by its progressive clinical course, changing clinical and histopathologic features, and potential to develop into cancer. PVL behaves in a more aggressive and relentless manner than the more innocuous white oral lesions that it can resemble clinically. We present three cases of PVL that progressed to carcinoma and discuss the histopathologic findings that may either hinder or assist in the diagnosis.

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What this paper is about

Proliferative verrucous leukoplakia (PVL) is a distinct clinical form of oral leukoplakia defined by its progressive clinical course, changing clinical and histopathologic features, and potential to develop into cancer. PVL behaves in a more aggressive and relentless manner than the more innocuous white oral lesions that it can resemble clinically. We present three cases of PVL that progressed to carcinoma and discuss the histopathologic findings that may either hinder or assist in the diagnosis.

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OpenAlex reports 53 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Proliferative verrucous leukoplakia (PVL) is a distinct clinical form of oral leukoplakia defined by its progressive clinical course, changing clinical and histopathologic features, and potential to develop into cancer. PVL behaves in a more aggressive and relentless manner than the more innocuous white oral lesions that it can resemble clinically. We present three cases of PVL that progressed to carcinoma and discuss the histopathologic findings that may either hinder or assist in the diagnosis.

Key concepts: Verrucous carcinoma, Leukoplakia, Medicine, Carcinoma, Dermatology, Cancer, Pathology, Oral leukoplakia

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