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2010•Pharmaceutical Sciences EncyclopediaRequires access

Randomized Controlled Trials

Giuseppe Garcea, David P. Berry

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Abstract

Abstract A randomized controlled trial (RCT) is a study in which subjects are allocated at random to receive one of two possible interventions. RCT provides an unbiased, balanced, and reliable method of determining the efficacy of new drugs or devices. This article focuses on the different methodologies applied in RCTs and their potential flaws.

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What this paper is about

Abstract A randomized controlled trial (RCT) is a study in which subjects are allocated at random to receive one of two possible interventions. RCT provides an unbiased, balanced, and reliable method of determining the efficacy of new drugs or devices. This article focuses on the different methodologies applied in RCTs and their potential flaws.

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Available abstract

Abstract A randomized controlled trial (RCT) is a study in which subjects are allocated at random to receive one of two possible interventions. RCT provides an unbiased, balanced, and reliable method of determining the efficacy of new drugs or devices. This article focuses on the different methodologies applied in RCTs and their potential flaws.

Key concepts: Randomized controlled trial, Randomized response, N of 1 trial, Medicine, Computer science, Medical physics, Statistics, Mathematics

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