2009Chemical ReviewsOpen access

Fundamental Aspects of Protein−Protein Association Kinetics

Gideon Schreiber, Gilad Haran, Huan‐Xiang Zhou

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Abstract

ADVERTISEMENT RETURN TO ISSUEReviewNEXTFundamental Aspects of Protein−Protein Association KineticsG. Schreiber*†, G. Haran*‡, and H.-X. Zhou*§View Author Information Departments of Biological Chemistry and Chemical Physics, Weizmann Institute of Science, Rehovot, 76100, Israel and Department of Physics and Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida 32306* To whom correspondence should be addressed. G.S.: phone, +972-8-9343249; fax, +972-8-9346095; e-mail, [email protected]. G.H.: phone, +972-8-9342625; fax, +972-8-9342749; e-mail, [email protected]. H.-X.Z.: phone, 850-6451336; fax, 850-6447244; e-mail, [email protected]†Department of Biological Chemistry, Weizmann Institute of Science.‡Department of Chemical Physics, Weizmann Institute of Science.§Florida State University.Cite this: Chem. Rev. 2009, 109, 3, 839–860Publication Date (Web):February 5, 2009Publication History Received22 May 2008Published online5 February 2009Published inissue 11 March 2009https://pubs.acs.org/doi/10.1021/cr800373whttps://doi.org/10.1021/cr800373wreview-articleACS PublicationsCopyright © 2009 American Chemical SocietyRequest reuse permissionsArticle Views12611Altmetric-Citations577LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Diffusion,Genetics,Kinetic parameters,Kinetics,Molecular mechanics Get e-Alerts

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ADVERTISEMENT RETURN TO ISSUEReviewNEXTFundamental Aspects of Protein−Protein Association KineticsG. Schreiber*†, G. Haran*‡, and H.-X. Zhou*§View Author Information Departments of Biological Chemistry and Chemical Physics, Weizmann Institute of Science, Rehovot, 76100, Israel and Department of Physics and Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida 32306* To whom correspondence should be addressed. G.S.: phone, +972-8-9343249; fax, +972-8-9346095; e-mail, [email protected]. G.H.: phone, +972-8-9342625; fax, +972-8-9342749; e-mail, [email protected]. H.-X.Z.: phone, 850-6451336; fax, 850-6447244; e-mail, [email protected]†Department of Biological Chemistry, Weizmann Institute of Science.‡Department of Chemical Physics, Weizmann Institute of Science.§Florida State University.Cite this: Chem. Rev. 2009, 109, 3, 839–860Publication Date (Web):February 5, 2009Publication History Received22 May 2008Published online5 February 2009Published inissue 11 March 2009https://pubs.acs.org/doi/10.1021/cr800373whttps://doi.org/10.1021/cr800373wreview-articleACS PublicationsCopyright © 2009 American Chemical SocietyRequest reuse permissionsArticle Views12611Altmetric-Citations577LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Diffusion,Genetics,Kinetic parameters,Kinetics,Molecular mechanics Get e-Alerts

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ADVERTISEMENT RETURN TO ISSUEReviewNEXTFundamental Aspects of Protein−Protein Association KineticsG. Schreiber*†, G. Haran*‡, and H.-X. Zhou*§View Author Information Departments of Biological Chemistry and Chemical Physics, Weizmann Institute of Science, Rehovot, 76100, Israel and Department of Physics and Institute of Molecular Biophysics, Florida State University, Tallahassee, Florida 32306* To whom correspondence should be addressed. G.S.: phone, +972-8-9343249; fax, +972-8-9346095; e-mail, [email protected]. G.H.: phone, +972-8-9342625; fax, +972-8-9342749; e-mail, [email protected]. H.-X.Z.: phone, 850-6451336; fax, 850-6447244; e-mail, [email protected]†Department of Biological Chemistry, Weizmann Institute of Science.‡Department of Chemical Physics, Weizmann Institute of Science.§Florida State University.Cite this: Chem. Rev. 2009, 109, 3, 839–860Publication Date (Web):February 5, 2009Publication History Received22 May 2008Published online5 February 2009Published inissue 11 March 2009https://pubs.acs.org/doi/10.1021/cr800373whttps://doi.org/10.1021/cr800373wreview-articleACS PublicationsCopyright © 2009 American Chemical SocietyRequest reuse permissionsArticle Views12611Altmetric-Citations577LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Diffusion,Genetics,Kinetic parameters,Kinetics,Molecular mechanics Get e-Alerts

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