2009•Journal of Clinical MicrobiologyOpen access
Nonhemolytic Streptococcus pyogenes Isolates That Lack Large Regions of the sag Operon Mediating Streptolysin S Production
Miho Yoshino, Somay Yamagata Murayama, Katsuhiko Sunaoshi, Takeaki Wajima, Miki Takahashi, Junko Masaki, Iku Kurokawa, Kimiko Ubukata
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Abstract
Among nonhemolytic Streptococcus pyogenes (group A streptococcus) strains (n = 9) isolated from patients with pharyngitis or acute otitis media, we identified three deletions in the region from the epf gene, encoding the extracellular matrix binding protein, to the sag operon, mediating streptolysin S production.