Effect of Administration of Thiamine, Riboflavin, Ascorbic Acid and Vitamin A to Students on Their Pantothenic Acid Contents in Serum and Urine

Combined administration of thiamine, riboflavin, pyridoxine, ascorbic acid, nicotinic acid, vitamin A and B12 to 20 students resulted in increase in the concentration of pantothenic acid in serum in 7 students and in decrease in 3 students. Effects of separate administration of thiamine, riboflavin, ascorbic acid or vitamin A on the level of serum pantothenic acid were also examined. It was found that the level could be increased considerably by the administration of thiamine alone. Riboflavin also increased the level but to a lesser extent. Similar patterns of the vitamin effect were also observed for the urinary excretion of pantothenic acid.