Baclofen in the short-term maintenance treatment of benzodiazepine dependence
Lekhansh Shukla, Arun Kandasamy, Muralidharan Kesavan, Vivek Benegal
Abstract
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Lekhansh Shukla, Arun Kandasamy, Muralidharan Kesavan, Vivek Benegal
Abstract
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Benzodiazepine (BZD) dependence is a significant public health problem. Apart from the long-term tapering doses of BZD, no others drugs are available for the maintenance treatment of BZD dependence. Baclofen has been used in alcohol and other drug dependence as long-term anti-craving agent. Since alcohol and BZD act through the GABA receptor, we attempted to study the effect of Baclofen as maintenance treatment in a series of five cases with BZD dependence.
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Benzodiazepine (BZD) dependence is a significant public health problem. Apart from the long-term tapering doses of BZD, no others drugs are available for the maintenance treatment of BZD dependence. Baclofen has been used in alcohol and other drug dependence as long-term anti-craving agent. Since alcohol and BZD act through the GABA receptor, we attempted to study the effect of Baclofen as maintenance treatment in a series of five cases with BZD dependence.
Key concepts: Baclofen, Benzodiazepine, Medicine, Craving, Alcohol dependence, Term (time), Psychiatry, Anesthesia