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2008•Nature MedicineRequires access

Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing

Jin Li, Lilin Wang, Harvey J. Mamon, Matthew H. Kulke, Ross I. Berbeco, Gerassimos Mike Makrigiorgos

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Key concepts: COLD-PCR, Genotyping, Biology, Variants of PCR, Polymerase chain reaction, Genotype, Genetics, Multiple displacement amplification

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Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing — Research Paper | ScholarLens