2015•International Journal of PharmaceuticsRequires access

Optimization of a pharmaceutical tablet formulation based on a design space approach and using vibrational spectroscopy as PAT tool

Pierre-François Chavez, Pierre Lebrun, Pierre‐Yves Sacré, Charlotte De Bleye, Lauranne Netchacovitch, Serge Cuypers, Jérôme Mantanus, Henri Motte, Martin Alexander Schubert, Brigitte Évrard, Philippe Hubert, Eric Ziémons

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Key concepts: Critical quality attributes, Quality by Design, Process analytical technology, Design of experiments, Active ingredient, Process engineering, Computer science, Particle size