2008•Clinical Infectious DiseasesRequires access

FebrilePlasmodium falciparumMalaria 4 Years after Exposure in a Man with Sickle Cell Disease

Tatiana von Bahr Greenwood, Tomas Vikerfors, Maria Sjöberg, Gunnar Skeppner, Anna Färnert

Abstract

We report a case of symptomatic Plasmodium falciparum malaria that manifested 4 years after a visit to an area of endemicity in an 18-year-old male patient with sickle cell disease. The exceptionally long incubation time raises the questions of how and where P. falciparum parasites can reside for several years before suddenly causing disease.

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Key concepts: Malaria, Plasmodium falciparum, Medicine, Disease, Sickle cell trait, Pediatrics, Immunology, Hemoglobinopathy