2007•ARKIVOCOpen access

Solvent-free liquid-phase synthesis of polyhydroquinoline derivatives under microwave irradiation

Xiaolan Zhang, Shou‐Ri Sheng, Xian-Liang Liu, Xiaoling Liu

Abstract

Polyhydroquinoline derivatives have been efficiently prepared on polyethylene glycol (PEG) via one-pot condensation of PEG-bound acetoacetate, 1,3-cyclohexanedione, ammonium acetate and the appropriate aromatic aldehyde in the presence of catalytic amounts of polyphosphoric acid by solvent-free microwave irradiation.The procedure provided the target compounds in excellent yield and purity with a facile work-up procedure.

Open-access reader

About this research paper

What this paper is about

Why it matters

OpenAlex reports 23 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Chemistry, Microwave irradiation, Microwave, Phase (matter), Liquid phase, Irradiation, Combinatorial chemistry, Chromatography